Abactum-500/Abactum-250 is the medicine manufactured of Cefuroxime Axetil IP eq to Cefuroxime.


Granisetron hydrochloride is the drug used to treat nausea and vomiting especially with particular types of cancer chemotherapy and radiation.

Chemistry of Cefuroxime Axetil IP

Chemical Formula: C20H22N4O10S

Molecular Mass: 510.48

Physical Properties:White powder

Pharmacokinetics of Cefuroxime Axetil IP

Absorption: After the oral administration of cefuroxime axetil, the drug is absorbed from the GI tract as the 1-(acetyloxy) ethyl ester and rapidly hydrolyzed to cefuroxime.

Distribution: Cefuroxime axetil is extensively distributed into body tissues and fluids including joint fluid, bile, bone, pleural fluid, sputum, and aqueous humor

Elimination: Cefuroxime is excreted unaffected in the urine; in adults, about 50% of the administered dose is recovered in the urine within 12 hours.

Pharmacodynamics of Cefuroxime Axetil IP

Cefuroxime has bactericidal activity against an extensive range of general pathogens, including many beta-lactamase–producing strains. Cefuroxime is stable to many bacterial beta-lactamases, particularly plasmid-mediated enzymes that are commonly found in enterobacteriaceae.

Medical uses of Cefuroxime Axetil IP

Cefuroxime Axetil IP has following medical use:

  • To prevent from Haemophilus influenzae
  • To prevent from Neisseria gonorrhoeae
  • To treat Lyme disease
  • Uncomplicated Skin and Skin-Structure Infections
  • Uncomplicated Urinary Tract Infections
  • Side effects of Cefuroxime Axetil IP

    It could have following minor as well as serious side effects:

  • Diarrhea that is watery or bloody
  • Fever, chills, body aches
  • Chest pain
  • Pounding heartbeats
  • Unusual bleeding
  • Blood in urine
  • Pale or yellowed skin
  • Dark colored urine
  • Overdose of Cefuroxime Axetil IP

    Overdose of cefuroxime may cause cerebral irritation leading to convulsions; so, immediate medical treatment is needed.

    Cautions of Cefuroxime Axetil IP

    The drug Cefuroxime Axetil IP may cause you dizzy or drowsy; so, do not drive, do not use heavy machinery, or do not involve in any activity that requires alertness until you are confident you can perform such activities safely.