Aloten 50

Aloten or Atenolol is the medicine belongs to the group of β-blockers and commonly used in cardiovascular diseases.

Chemistry of Atenolol

Chemical Formula: C14H22N2O3

Molecular Mass: 266.336 g/mol

Pharmacokinetics of Atenolol

Atenolol (100 & 200 mg orally) is rapidly absorbed, reductions in heart rate and systolic pressure being observed in merely 30 minutes. And, the effect persists for up to 8 hours.

Furthermore, more than 85% of an intravenous dose is excreted in urine within 24 hours but only 50% of an oral dose.

Pharmacodynamics Atenolol

The bioavailability of roughly 50% is due to reduced absorption. Peak blood levels are observed at 2 to 4 hours and the half life of Atenolol given orally is 5 to 6 hours. Likewise, Atenolol reduces the cardiac response to standing and head-up tilt.

Medical uses of Atenolol

Atenolol has the following medical uses:

  • Hypertension
  • Angina
  • Supraventricular Tachycardia
  • Acute Myocardial Infarction
  • Ventricular Tachycardia
  • Side Effects of Atenolol

    Atenolol may cause range of side effects some of them are casual and some of them may be serious; but when it is serious, patient needs to take quick treatment. Minor side effects:

  • Indigestion
  • Constipation
  • Dry mouth
  • Dizziness or faintness
  • Cold Extremities
  • Impotence
  • Rhinitis
  • Hair Loss
  • Confusion
  • Depression
  • Insomnia
  • Nightmares
  • Fatigue
  • Weakness
  • Serious Side effects:

  • Hallucinations
  • Low blood pressure
  • Skin reactions
  • Sensation of 'pins and needles' in hands or feet
  • Visual disturbances
  • Hearing problem
  • Speaking problem
  • Overdose of Atenolol

    The symptom of overdose of Atenolol may be severe or may be minor; however, in any case you are needed to take precaution and consult your doctor. Some of the symptoms of overdose are:

  • Bradycardia
  • Severe Hypertension with shock
  • Acute heart failure
  • Hypoglycemia
  • Bronchospastic Reactions
  • Caution of Atenolol

    Atenolol should not be taken with orange juice because it can interfere with its uptake.