Alzine-L is the drug composed of Levocetirizine Dihydrochloride.


Levocetirizine Dihydrochloride is a drug that is used for the treatment and management of symptoms related to allergies.

Chemistry of Cetirizine Dihydrochloride

Chemical Formula: C21H25ClN2O3.2(HCl)

Molecular Mass: 461.81

Physical Properties: White crystalline powder

Solubility: Soluble in water

Pharmacokinetics of Levocetirizine Dihydrochloride

Absorption: Rapidly and extensively absorbed and steady state achieved after 2 days.

Distribution: Plasma protein binding is about 92%. Vd is about 0.4 L/kg.

Metabolism: Metabolism is less than 14% and by aromatic oxidation.

Elimination: The half-life is between 8 and 9 hours and the elimination is 85.4% and 12.9% through urine and feces, respectively.

Pharmacodynamics of Levocetirizine Dihydrochloride

Levocetirizine Dihydrochloride medicines are formulated as immediate discharge; white, film-coated, oval-shaped tablets manufactured especially for oral administration. Its inactive ingredients are: microcrystalline cellulose, colloidal anhydrous silica, lactose monohydrate, and magnesium stearate.

Medical uses of Levocetirizine Dihydrochloride

Levocetirizine Dihydrochloride has following medical use:

  • Used for seasonal and perennial allergic rhinitis
  • Used for the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Side effects of Levocetirizine Dihydrochloride

    Though, Levocetirizine dihydrochloride is well tolerated; however, it could have following minor as well as serious side effects:

  • Severe drowsiness that interferes with your daily activities
  • Overdose of Levocetirizine Dihydrochloride

    There are following symptoms of Levocetirizine dihydrochloride overdose:

  • Agitation
  • Restlessness
  • Drowsiness
  • Cautions of Levocetirizine Dihydrochloride

    Do not take Levocetirizine Dihydrochloride if you have had an allergic reaction of this drug and also it is not suggested to take alcohol or use medicines that may cause drowsiness while you are taking Levocetirizine Dihydrochloride.